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Welcome!


I am an Assistant Professor at the Genetics Laboratory at the Biotechnology Department of the Agricultural University of Athens. My main scientific interests include the investigation of genetic polymorfisms, genetic variability in viral strains and the in silico drug design of novel antiviral and anticancer agents.
I graduated from Bedfordshire University, London with a honour’s degree in Biology and Biochemistry. Soon after that I moved to Wales, where I received my Master’s degree in Molecular Modelling and Quantum Chemistry at the Chemistry School, Cardiff University, after having secured a full EPSRC scholarship. At this stage, I was awarded a three-year full time PhD studentship from the Pharmacy Department of Cardiff University. As a result, three years later I successfully defended my PhD in Viral Genetics and Antiviral Drug Design, under the supervision of Prof Andrea Brancale. I was blessed with collaborations and co-supervision from Prof Colin Berry in Molecular Biology and Genetics (School of Life Sciences) and Prof Chris McGuigan in Medicinal Chemistry (School of Pharmacy).
During my postdoctoral training and later as senior researcher I continued to investigate the genetic elasticity of viral genomes (antigenic drift/shift). To date I am still fascinated by the rate of mutagenesis and amount of genetic rearrangements that viral species can tolerate and still survive. That is the main reason that I chose to focus my research on the flaviviridae viral family, which is a super-highly mutagenic and diverse viral family, mainly due to the fact that flaviviridae are single stranded RNA viruses and completely lack any kind of genomic proofreading machinery. Traditional genetic approaches fail to keep up, as sequence conservation among strains of the flaviviridae family can drop to less than 20% sequence identity. Our research is fixated on the investigation of alternative approaches to efficiently study viral genetics, mainly by the multimodal fusion of information from genetic, structural and physicochemical analysis. In order to achieve this we use a repertoire of techniques that range from DNA manipulation, SDM, Cloning, Expression and Purification, all the way to Computational Biology, Molecular Modelling and Bioinformatics.
At the same time, I remain a research associate at the Multidimensional Data Analysis & Knowledge Management Laboratory at the Computer Engineering and Informatics Department of the University of Patras, as well as an affiliate researcher to the Biomedical Research Foundation of the Academy of Athens. Finally, I was recently appointed adjunct investigator at the Bioinformatics Department at King’s College London and I remain, for the 5th consecutive year, the Editor in Chief of the (International & Peer-Reviewed) Journal of Molecular Biochemistry. To date I have published 90 peer-reviewed original research articles, 5 monograph ISBN books, 2 international scientific patents, and have been on the receiving end of numerous grants and awards.





Scientific Highlights:

90 Published Articles in Peer-Reviewed International journals
47 Published Articles indexed in PubMed
36 Full Articles Published in Conference Proceeding
13 Software Packages Developed for Genetic and Structural Analysis
11 Published Articles indexed in DBLP (Computer Science)
5 Scientific Monograph Books
2 International Patents
492 Citations | h-index: 12 | i10-index: 15
 
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